Recombinant Mouse Fasciculation and elongation protein zeta-1 (Fez1) from MyBioSource.com

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Recombinant Mouse Fasciculation and elongation protein zeta-1 (Fez1)

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Description

This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described